Houston's Fifth Ward has been a drug corridor for decades, and this episode of the Drugs, Inc. series goes into it to trace how crack cocaine, prescription cough syrup, and street-level violence move through the neighborhood. A working crack dealer describes the economics of his trade, a member of a Hispanic street gang explains the territory disputes that come with it, and a pimp and several addicts lay out how the drug and sex trades overlap in the same blocks. A full-patch member of the Aryan Brotherhood of Texas speaks about the prison gang's role in distribution once dealers are locked up. The film also tracks the local popularity of "lean," a codeine-based cough syrup mixed into soft drinks, walking through why it spread and what it does to the people using it. Interviews are shot on the streets and in homes where the trade actually happens, giving the episode a street-level view of addiction and dealing rather than a policy overview.