In his new book The Moral Landscape, neuroscientist and philosopher Sam Harris challenges the commonly held view that science has nothing to say about moral issues and that religion is the best authority on meaning, values and a good life. For Sam, the goal of The Moral Landscape is to begin a conversation about how moral truth can be understood in terms of science. Richard Dawkins is known for his persistence in demanding a rational and scientific approach to solving life’s most fundamental questions wherever and whenever it can be applied. So, can science help us to determine how we should live in the 21st century? These two pinnacles of rationalist thought discuss at The Sheldonian Theatre, University of Oxford, how the science of morality might be formulated and applied to human well-being.