Sweet Remedy picks up where Sweet Misery: A Poisoned World left off, moving past aspartame to look at the broader range of additives in the American food supply and the regulatory system that allows them. The film argues that food and drug agencies work alongside corporate interests to shape public opinion rather than police safety, and it traces the money spent marketing additives that the film's interviewees describe as neuro-toxic. Dr. Joseph Mercola and Dr. Candace Pert speak to the physiological effects of these ingredients, GMO campaigner Jeffrey Smith addresses genetically modified food, and Noam Chomsky weighs in on the corporate messaging machine behind it all. Actor Larry Hagman appears among the film's witnesses as well. Alongside the indictment, the film profiles grassroots groups working to grow, source, and prepare food outside that system, framing those efforts as the practical alternative to a supply chain it considers compromised. The film's case rests entirely on its interview subjects rather than independent data or regulatory documents shown on screen.