Soliris treats a handful of rare, life-threatening blood disorders, and it carries a price tag near half a million dollars a year, making it the most expensive drug in the world. This film follows patients who depend on it to survive and who are now pushing their government to cover the cost, against a drugmaker, Alexion, that has little incentive to lower the price and a health system unsure it can afford to pay it. Interviews with patients and their families lay out what happens when the medication stops: relapse, organ damage, sometimes death, and the film uses that fact to press its central question of who should bear the cost of a treatment this expensive when the alternative is watching someone die. Officials and industry voices weigh in on drug pricing, patent protection, and the economics of manufacturing a treatment for a disease so rare that only a small number of people will ever need it, leaving the standoff between patients, government, and pharmaceutical profit unresolved.