Part of Yale's open course Understanding Medical Research: Your Facebook Friend is Wrong, this lecture examines fraud in medical research. The instructor walks through how fabricated or manipulated data slip past peer review, citing patterns seen in retracted studies and the incentives, career pressure, funding, publication quotas, that push some researchers to falsify results. The talk covers how fraud is typically detected, from statistical irregularities to whistleblowers and data audits, and what happens once a paper is retracted, including how long false claims can keep circulating in the literature and the media before correction. The lecture fits into the course's broader project of teaching viewers to read health claims skeptically, treating fraud as one of several failure modes, alongside bias and bad statistics, that make some published medical research unreliable. Concise and example driven rather than theoretical.