Experimental Molecular Genetics
MIT's project-based laboratory course puts students directly into original molecular genetics research rather than scripted experiments. The semester centers on chemical genetics using the roundworm Caenorhabditis elegans as a model organism, with students designing research rationale, planning experiments, executing them at the bench, and then communicating results as a working scientist would. The course targets undergraduates, including sophomores, who are considering a career in biomedical research, and it emphasizes modern molecular biology and genetics techniques throughout. Materials include the course's lab framework and safety guidance, since the experiments involve real hazards requiring proper training, facilities, and supervision. This is MIT OpenCourseWare, so the published materials are the actual course structure and readings rather than a summary, though there is no certificate and no live instructor support. It suits a self-directed learner who wants to see how a research-based lab course is organized, more than someone looking for a passive video lecture series.