Yale professor Tamar Gendler continues her course Philosophy and the Science of Human Nature with a lecture on Stoic detachment. She opens with Epictetus's distinction between what is up to us and what is not, arguing that happiness depends on shifting focus from external outcomes to our own attitudes and interpretations. Gendler lays out three pieces of Epictetus's practical advice for cultivating detachment, illustrated with contemporary examples, then turns to Boethius's Consolation of Philosophy for a related take on fortune and inner freedom. The lecture closes with Admiral James Stockdale, whose application of Stoic detachment as a prisoner of war during Vietnam serves as a real-world test of the philosophy's claims. Recorded in Spring 2011 as part of Yale's PHIL 181, the talk moves from ancient texts to modern psychological framing of resilience and control.