Richard Skolnik, lecturer at Yale and author of Global Health 101, looks at how science and technology can address the global health challenges expected over the next few decades. Part of his Essentials of Global Health course on Coursera, this lesson surveys emerging tools such as new vaccines, diagnostics, and digital health platforms, and argues that technical breakthroughs only matter if paired with collective action, funding, and political will. Skolnik walks through examples of how innovation has changed disease control before, then turns to the barriers that keep promising technologies from reaching the people who need them most, including weak health systems and uneven global investment. The lecture is plainly delivered, slide-driven, and aimed at students building a broad foundation in global health rather than specialists, closing with a case for treating science and technology as tools within a larger system of governance and cooperation rather than solutions on their own.